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1

Cyclin-dependent protein kinase 2 activity is required for mitochondrial translocation of Bax and disruption of mitochondrial transmembrane potential during etoposide-induced apoptosis

Joon-Seok Choi, Soona Shin, Ying Hua Jin, Hyungshin Yim, Kyo-Tan Koo, Kwang-Hoon Chun, You-Take Oh, Won Hee Lee, Seung-Ki Lee

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 809 KB

english, 2007

2

Cdk2 acts upstream of mitochondrial permeability transition during paclitaxel-induced apoptosis

Xiao-Xi Guo, Hanna Kim, Yang Li, Hyungshin Yim, Seung Ki Lee, Ying-Hua Jin

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 611 KB

english, 2011

3

DNA-binding and regulatory properties of the transcription factor and putative tumor suppressor p150Sal2

Hongcang Gu, Dawei Li, Chang K. Sung, Hyungshin Yim, Philip Troke, Thomas Benjamin

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Année:

2011

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2011

4

ATR (AT mutated Rad3 related) activity stabilizes Cdc6 and delays G2/M-phase entry during hydroxyurea-induced S-phase arrest of HeLa cells

Linhua Liu, Jae Hyuk Choi, Hyungshin Yim, Joon Seok Choi, Byoung Duck Park, Seung Ju Cho, Seung Ki Lee

Journal:

The International Journal of Biochemistry & Cell Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2009

5

Cdk2 activity is associated with depolarization of mitochondrial membrane potential during apoptosis

Ying Hua Jin, Hyungshin Yim, Jeong Hill Park, Seung Ki Lee

Journal:

Biochemical and Biophysical Research Communications

Année:

2003

Langue:

english

Fichier:

PDF, 338 KB

english, 2003

6

The accumulation of DNA repair defects is the molecular origin of carcinogenesis

Cha, Hyuk-Jin, Yim, Hyungshin

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 298 KB

english, 2013

7

Two nuclear export signals of Cdc6 are differentially associated with CDK-mediated phosphorylation residues for cytoplasmic translocation

Hwang, In Sun, Woo, Sang Uk, Park, Ji-Woong, Lee, Seung Ki, Yim, Hyungshin

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2014

Langue:

english

Fichier:

PDF, 2.24 MB

english, 2014

8

Plk1-targeted therapies in TP53- or RAS-mutated cancer

Yim, Hyungshin, Erikson, Raymond L.

Journal:

Mutation Research/Reviews in Mutation Research

Année:

2014

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2014

9

ATM kinase promotes both caspase-8 and caspase-9 activation during TNF-α-induced apoptosis of HeLa cells

Liu, Linhua, Yim, Hyungshin, Choi, Jae Hyuk, Kim, Seung-Tak, Jin, Yinghua, Lee, Seung Ki

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2014

10

Predictive value of urinary and serum biomarkers in young children with febrile urinary tract infections

Yim, Hyung Eun, Yim, Hyungshin, Bae, Eun Soo, Woo, Sang Uk, Yoo, Kee Hwan

Journal:

Pediatric Nephrology

Année:

2014

Langue:

english

Fichier:

PDF, 503 KB

english, 2014

11

Cleavage of Cdc6 by Caspase-3 Promotes ATM/ATR Kinase-Mediated Apoptosis of HeLa Cells

Hyungshin Yim, In Sun Hwang, Joon-Seok Choi, Kwang-Hoon Chun, Ying Hua Jin, Young-Mi Ham, Kwang Youl Lee and Seung Ki Lee

Journal:

The Journal of Cell Biology

Année:

2006

Langue:

english

Fichier:

PDF, 2.47 MB

english, 2006

12

A mouse polyomavirus-encoded microRNA targets the cellular apoptosis pathway through Smad2 inhibition

Sung, Chang Kyoo, Yim, Hyungshin, Andrews, Erik, Benjamin, Thomas L.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2014

13

Phosphorylation of Cdc6 at serine 74, but not at serine 106, drives translocation of Cdc6 to the cytoplasm

Yim, Hyungshin, Park, Ji-Woong, Woo, Sang Uk, Kim, Seong-Taek, Liu, Linhua, Lee, Chul-Hoon, Lee, Seung Ki

Journal:

Journal of Cellular Physiology

Année:

2013

Langue:

english

Fichier:

PDF, 1.90 MB

english, 2013

14

Synergistic effect of simvastatin plus NS398 on inhibition of proliferation and survival in hepatocellular carcinoma cell line

Lee, Sun Jae, Hwang, Ji Won, Yim, Hyungshin, Yim, Hyung Joon, Woo, Sang Uk, Suh, Sang Jun, Hyun, Jong Jin, Jung, Sung Woo, Koo, Ja Seol, Kim, Ji Hoon, Seo, Yeon Seok, Yeon, Jong Eun, Lee, Sang Woo, By

Journal:

Journal of Gastroenterology and Hepatology

Année:

2014

Langue:

english

Fichier:

PDF, 1003 KB

english, 2014

15

The tumor suppressor protein p150Sal2in carcinogenesis

Sung, Chang Kyoo, Yim, Hyungshin

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 678 KB

english, 2015

16

Current clinical trials with polo-like kinase 1 inhibitors in solid tumors

Journal:

Anti-Cancer Drugs

Année:

2013

Langue:

english

Fichier:

PDF, 405 KB

english, 2013

17

Emodin, an Anthraquinone Derivative Isolated from the Rhizomes of Rheum palmatum, Selectively Inhibits the Activity of Casein Kinase II as a Competitive Inhibitor

Yim, Hyungshin, Lee,, Chul Hoon Lee, Yong Hee, Lee, Seung Ki

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 111 KB

english, 1999

18

Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase

Hyungshin Yim and Raymond L. Erikson

Journal:

Proceedings of the National Academy of Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2010

19

Antiinflammatory and analgesic effects ofEurycoma longifoliaextracts

Han, Young Min, Woo, Sang-Uk, Choi, Min Sun, Park, Yu Na, Kim, Seung Hyun, Yim, Hyungshin, Yoo, Hye Hyun

Journal:

Archives of Pharmacal Research

Année:

2016

Langue:

english

Fichier:

PDF, 891 KB

english, 2016

20

Regulation of the final stage of mitosis by components of the pre-replicative complex and a polo kinase

Yim, Hyungshin, Erikson, Raymond L.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 942 KB

english, 2011

21

Differential Cellular Effects of Plk1 Inhibitors Targeting the ATP-binding Domain or Polo-box Domain

Shin, Sol-Bi, Woo, Sang-Uk, Yim, Hyungshin

Journal:

Journal of Cellular Physiology

Année:

2015

Langue:

english

Fichier:

PDF, 3.89 MB

english, 2015

22

Sensitivity of TP53 -Mutated Cancer Cells to the Phytoestrogen Genistein Is Associated with Direct Inhibition of Plk1 Activity

Shin, Sol-Bi, Woo, Sang-Uk, Chin, Young Won, Jang, Young-Joo, Yim, Hyungshin

Journal:

Journal of Cellular Physiology

Année:

2016

Langue:

english

Fichier:

PDF, 2.16 MB

english, 2016

23

Analysis of Cyclin-Dependent Kinase 2-Regulated Phosphorylation of Stathmin in Etoposide-Induced Apoptotic HeLa Cells by Two-Dimensional Electrophoresis and Mass Spectrometry

Kim, Yong-ung, Koo, Kyo-Tan, Choi, Joon-Seok, Jin, Ying-Hua, Yim, Hyungshin, Oh, You-Take, Lee, Seung Ki

Journal:

JOURNAL OF HEALTH SCIENCE

Année:

2005

Langue:

english

Fichier:

PDF, 793 KB

english, 2005

24

Roles ofSALL2in tumorigenesis

Sung, Chang K., Yim, Hyungshin

Journal:

Archives of Pharmacal Research

Année:

2017

Langue:

english

Fichier:

PDF, 728 KB

english, 2017

25

Oligopeptide Competition Assay for Phosphorylation Site Determination

Joo, Min Sung, Koo, Ja Hyun, Shin, Sol-Bi, Yim, Hyungshin, Kim, Sang Geon

Journal:

Journal of Visualized Experiments

Année:

2017

Langue:

english

Fichier:

PDF, 346 KB

english, 2017

26

The Polyoma Virus Large T Binding Protein p150 Is a Transcriptional Repressor of c-MYC

Sung, Chang Kyoo, Yim, Hyungshin, Gu, Hongcang, Li, Dawei, Andrews, Erik, Duraisamy, Sekhar, Li, Cheng, Drapkin, Ronny, Benjamin, Thomas, Rishi, Arun

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 542 KB

english, 2012

27

7-O-Methylwogonin from Scutellaria baicalensis Disturbs Mitotic Progression by Inhibiting Plk1 Activity in Hep3B Cells

Woo, Sang-Uk, Jang, Hay-Ran, Chin, Young-Won, Yim, Hyungshin

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 367 KB

english, 2018

28

53BP1 A guardian for centrosomal integrity

Journal:

Frontiers in Bioscience

Année:

2018

Langue:

english

Fichier:

PDF, 876 KB

english, 2018

29

Nrf2-lncRNA controls cell fate by modulating p53-dependent Nrf2 activation as an miRNA sponge for Plk2 and p21 cip1

Joo, Min Sung, Shin, Sol-Bi, Kim, Eun Jung, Koo, Ja Hyun, Yim, Hyungshin, Kim, Sang Geon

Journal:

The FASEB Journal

Année:

2019

Fichier:

PDF, 2.97 MB

2019

30

Nrf2-lncRNA controls cell fate by modulating p53-dependent Nrf2 activation as an miRNA sponge for Plk2 and p21 cip1

Joo, Min Sung, Shin, Sol-Bi, Kim, Eun Jung, Koo, Ja Hyun, Yim, Hyungshin, Kim, Sang Geon

Journal:

The FASEB Journal

Année:

2019

Langue:

english

Fichier:

PDF, 2.97 MB

english, 2019

31

Molecular Targets of Genistein and Its Related Flavonoids to Exert Anticancer Effects

Chae, Hee-Sung, Xu, Rong, Won, Jae-Yeon, Chin, Young-Won, Yim, Hyungshin

Journal:

International Journal of Molecular Sciences

Année:

2019

Langue:

english

Fichier:

PDF, 473 KB

english, 2019

32

Cotargeting Plk1 and androgen receptor enhances the therapeutic sensitivity of paclitaxel-resistant prostate cancer

Shin, Sol-Bi, Woo, Sang-Uk, Yim, Hyungshin

Journal:

Therapeutic Advances in Medical Oncology

Année:

2019

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2019

33

Roles of the Phosphorylation of Transcriptional Factors in Epithelial-Mesenchymal Transition

Xu, Rong, Won, Jae-Yeon, Kim, Chang-Hyeon, Kim, Da-Eun, Yim, Hyungshin

Journal:

Journal of Oncology

Année:

2019

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2019

34

Roles of the Phosphorylation of Transcriptional Factors in Epithelial-Mesenchymal Transition

Xu, Rong, Won, Jae-Yeon, Kim, Chang-Hyeon, Kim, Da-Eun, Yim, Hyungshin

Journal:

Journal of Oncology

Année:

2019

Fichier:

PDF, 1.92 MB

2019

35

Active PLK1-driven metastasis is amplified by TGF-β signaling that forms a positive feedback loop in non-small cell lung cancer

Shin, Sol-Bi, Jang, Hay-Ran, Xu, Rong, Won, Jae-Yeon, Yim, Hyungshin

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 5.15 MB

english, 2019

36

Correction: Active PLK1-driven metastasis is amplified by TGF-β signaling that forms a positive feedback loop in non-small cell lung cancer

Shin, Sol-Bi, Jang, Hay-Ran, Xu, Rong, Won, Jae-Yeon, Yim, Hyungshin

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 212 KB

english, 2019

37

Correction: Active PLK1-driven metastasis is amplified by TGF-β signaling that forms a positive feedback loop in non-small cell lung cancer

Shin, Sol-Bi, Jang, Hay-Ran, Xu, Rong, Won, Jae-Yeon, Yim, Hyungshin

Journal:

Année:

2019

Fichier:

PDF, 212 KB

2019

38

CRISPR-mediated promoter de/methylation technologies for gene regulation

Sung, Chang K., Yim, Hyungshin

Journal:

Archives of Pharmacal Research

Année:

2020

Fichier:

PDF, 777 KB

2020

39

Combination of Inhibitors of USP7 and PLK1 has a Strong Synergism against Paclitaxel Resistance

Shin, Sol-Bi, Kim, Chang-Hyeon, Jang, Hay-Ran, Yim, Hyungshin

Journal:

International Journal of Molecular Sciences

Année:

2020

Fichier:

PDF, 2.34 MB

2020